Haugh AM, Witt JG, Hauch A, et al. Plast Reconstr Surg Glob Open. 2017;5(4)
Objective:
This meta-analysis reviewed randomized controlled trials (RCTs) comparing the efficacy of amniotic membrane products with standard wound care (SOC) for treating diabetic foot ulcers (DFUs).
Study Design:
The meta-analysis included five RCTs involving 259 patients with non-healing DFUs. The primary outcome was complete wound healing at 6 and 12 weeks. The review also included a cost analysis of amniotic membrane products compared to SOC.
Results:
The analysis showed that patients treated with amniotic products had a 2.75 times higher likelihood of complete wound healing compared to those receiving SOC alone. Additionally, the cost per healed DFU was significantly lower for amniotic membrane-treated patients compared to SOC alone.
Conclusion:
Amniotic membrane products significantly improve wound healing in DFUs and offer potential cost savings compared to standard care. This analysis highlights the value of amniotic membranes in promoting faster and more effective wound healing.
Link to Article:
Amnion Membrane in Diabetic Foot Wounds: A Meta-analysis